Hormone therapy of acne

Oral contraceptives may be a useful adjunctive therapy for all types of acne in women and adolescent girls. Sebum production is controlled by androgens, and oral contraceptives are known to reduce androgen levels. It is also important to know that oral antibiotics may decrease the effectiveness of oral contraceptives. Side effects from oral contraceptive use include nausea, vomiting, abnormal menses, weight gain, and breast tenderness.

II. Topical treatment

Topical mediations, those applied directly to the skin are available in many forms including gels, lotions, creams, soaps, or pads. Many years ago, empirical reliance was placed on the used of sulfur- and resorcinol-containing products, and to a degree, they are still used in the over-the counter market. Their mechanism of action has not been defined. Products containing salicylic acid, a keratolytic agent, have enjoyed some popularity. However, the major topical agents now in use are retinoid and antimicrobials such as benzoly peroxide and topical antibiotics.

Benzoyl peroxide works by killing bacteria and unclogging pores. It has an antibacterial effect and may also decrease the chemical reaction that changes the lining of the hair follicle. Benzoyl peroxide should not be applied at the same time of day as topical retinoid. Benzoyl peroxide may be used for mild case of comedones or to help prevent formation of other.

Topical retinoid , such as tretinoin, tazarotene, adapalene. They work by unclogging pores and reducing inflammation. They are intended for individuals with significant numbers of both open and closed comedones as well as papules and pustules. Tretinoin can be redness, peeling, irritating and photosensitivity ( high risk of sunburn ) . Most retinoid are applied at night and should not be used during pregnancy as they may cause harm to the fetus.

Antibiotics are also used for the treatment of acne, the most popular preparations containing erythromycin or clindamycin. They work by killing bacteria and reducing inflammation. They may be used to treat mild to moderate acne.

Azelaic acid is naturally occurring dicarboxylic acid found in cereal grains. It is available as a topical cream, with effective in inflammatory and comedonal acne. The activity of azelaic acid against inflammatory lesions may be greater than its activity against comedones. Azelaic acid is applied twice daily and its use is reported to have local side effects may include burning, warmth, stinging, tingling, itching, redness, dryness, peeling, or irritation while using azelaic acid topical.

III. Surgical and other Procedures

Drainage and Surgical Excision: Some large cysts, severely inflamed, extremely painful and similar to nodules do not respond to medication and may require drainage and extraction. Acne surgery is the term which refers to several surgical approaches for removing acne lesions. Dermatologists are trained in the proper technique and perform acne surgery under sterile conditions. These include opening up comedones and pimples by using a needle or small pointed blade and expressing the lesions with an extractor.

Intralesional Glucocorticoids: Intralesional injection of glucocorticoids, usually dramatically decreases the size of deep nodular lesions. The injection of a triamcinolone acetate suspension ( 2.5 to 10 mg/ml ) is recommended as the anti-inflammatory agent. This is a very useful form of therapy in the patient with nodular acne, but it often has to be repeated every 2 to 3 weeks.

Prevention acne…

1.Washing your hand before touching your face.

2.The simplest good deed you can do for your skin may surprise you; sleep! A healthy, well-rested body has the resources to build a strong immune

3.Stress often has a starring role in the ongoing acne drama. It has a huge impact, and it's becoming a bigger problem. When you become tense, your adrenal glands go work, flooding your bloodstream with the hormone cortisol. This triggers the sweat glands in your face to produce more oil. When your sebaceous glands go into high gear, there's a higher probability that this excess oil will mix with dead skin cells and clog your pores, trapping bacteria inside. More acne, primarily inflamed papules rather than blackheads or whiteheads.

4.Avoid the place that has more pollution i.e. dust, smoke or sunlight.

5.Acne cosmetica, or acne that is caused by cosmetics, is a mild and fairly common from acne. Because it is triggered by topical products rather than the complex process that creates true acne. If you have recently started using a new cosmetic and you are experiencing any of the symptoms ( i.e. rashy pink bumps on the cheeks, chin and forehead ) , discontinue use of the new product for a few days and see if your breakout subsides.

6.Do not squeeze or pick. Squeezing or picking your blemishes-with fingernails, pins or anything else – can force bacteria deeper into the skin, causing greater inflammation and infection. You will also increase the damage to the surrounding skin, so the blemish is more likely to leave a permanent scar.

7.Ta king mineral and vitamin for prevent skin from within.



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Copyright © 2006 Mega Lifesciences Pty Ltd., Last updated :Nov 2006.